Email: [email protected]
The head of the department is Honored Worker of Higher School of the Republic of Mordovia, Candidate of Medical Sciences, Professor Lyudmila Vladimirovna Novikova.
History of the department. The department was organized in 1968. The organizer and first head of the department was Professor Elena Afanasyevna Oleynikova, a major specialist in the field of applied and clinical immunology. Thanks to her efforts, organizational skills, connections with related departments of the country's leading medical institutes, the educational process was equipped and organized, the teaching methodology of the discipline and the directions of scientific research were determined.
Since 1989, the department has been headed by Professor L.V. Novikova, at the same time she is the scientific director of the Republican Center for Clinical Immunology, which was created by a joint order of the rector of the university and the Minister of Health of Mordovia.
Structure of the department. The Department of Immunology, Microbiology and Virology is located in building No. 13, occupies a separate room of 10 rooms on the 4th floor. It includes 3 educational microbiological laboratories, a clinical immunology laboratory with a total area of 116 sq.m., 2 educational and scientific rooms with computers, the head’s office with a department library, a teaching room, auxiliary rooms - a room for the preparation of nutrient media and sterilization of laboratory glassware with a box , autoclave, washing, laboratory.
The structure of the department includes a branch - the Mordovian Republican Center for Clinical Immunology. It is located in building No. 7 and includes a laboratory of cellular immunity factors, a laboratory of humoral immunity factors, an enzyme immunoassay laboratory, an office for receiving patients with diseases of the immune system, a microscopy and resident room.
The premises of the department are sufficient for conducting educational, educational, research and scientific work.
In terms of basic education, in terms of the level of scientific and pedagogical preparedness, the teaching staff of the department meets the requirements and content of training in the subject taught. Teachers are constantly working to improve their qualifications and teaching skills.
The Department of Immunology, Microbiology and Virology provides teaching of the following disciplines: a) “Microbiology and Virology” for 2-3 years of full-time study, specialties “General Medicine”, “Pediatrics” (Federal State Educational Standard III) b) “Immunology” - for 2-3 full-time courses, specialties "General Medicine", "Pediatrics" (FSES III), c) "Microbiology, immunology and virology" 3-4 courses of part-time study (GES II); d) "Clinical Immunology" - in 6-7 years in the specialties "General Medicine" and "Pediatrics", e) "Microbiology" - in 1-2 years in the specialty "Pharmacy".
The department is provided with standard programs for the disciplines; there are work programs developed by the department’s employees for all disciplines in typographical or typewritten form, approved at a meeting of the department in each current calendar year. The content of the work programs corresponds to the goals and objectives of training specialists in the specialties “General Medicine” and “Pediatrics”. The department has sets of educational and methodological documentation for the disciplines taught, including the following: a standard program, a work program, a calendar plan of lectures and practical classes, an examination program, independent work, a list of practical skills, a set of situational tasks and programmed control cards for individual classes , a computer control and training program used in individual sections of the subject, and test control in clinical immunology.
The educational process in the disciplines of the department is provided with the necessary educational literature in sufficient volume.
Head department, professor Novikova L.V. by decision of the Academic Council of the University dated November 30, 1990, the right of scientific supervisor was granted to applicants and graduate students in the specialty 14.00.38 (Allergology and Immunology). Scientific research is being conducted on the problem of “Immunopathogenesis of socially significant diseases of non-infectious etiology.”
At the department, in accordance with orders of the rector of the university and the Ministry of Health of the MASSR No. 1/158 of November 26, 1983 and No. 327 of November 4, 1983, a republican immunological center was created, the scientific director of which is the head. Department Associate Professor L.V. Novikova. The department and center are an important educational, research and production association. On the basis of the center, scientific research by the institute’s staff and practitioners, as well as theses, are carried out.
Employees of the department take an active part in the public life of the institute, university and city.
Doctor of Biological Sciences, Professor
Area of interest: study of differentiation antigens of human leukocytes, monoclonal antibodies.
Lecturer at the Department of Immunology, Faculty of Biology, Moscow State University. M.V. Lomonosov, teaches the course “Immunobiotechnology” for students of the department.
email:[email protected]
Mazurov Dmitry Vyacheslavovich
Trained from 2003 to 2007 at the National Cancer Institute in the USA (NCI-Frederick) in the laboratory of retrovirus replication under the leadership of David Derse.
Areas of interest: retrovirology, immunology, molecular biology, CRISPR-Cas9 genome editing system, quantitative assessment of intercellular transmission of HIV-1 and HTLV-1 viruses.
Romanova Alfira Ferdinandovna
Engineer
Toptygin Andrey Yurievich
Candidate of Medical Sciences, Leading Researcher
Area of scientific interests: immunochemistry, chromatography, isolation and modification of monoclonal antibodies, development of enzyme-linked immunosorbent diagnostic test systems.
Tsoi (Meshkova) Tatyana Dmitrievna
Trained in the laboratory of M. Bukrinsky George Washington University, Washington, USA.
Area of scientific interests: immunology, molecular biology, intracellular signaling.
Zotova (Shunaeva) Anastasia Andreevna
Postgraduate student at the Department of Immunology, Faculty of Biology, Moscow State University. M.V. Lomonosov
Graduate of the Department of Immunology, Faculty of Biology, Moscow State University. Works under the direction of D.V. Mazurova.
Trained in the laboratory of I. Lavrik of the Otto von Guericke University, Magdeburg, Germany, as well as in the laboratory of M. Bukrinsky George Washington University, Washington, USA.
Area of scientific interests: immunology, virology, molecular biology, CRISPR-Cas9 genome editing technology, virological synapse, intercellular infection of HIV-1 and HTLV-1, mechanisms of programmed cell death.
Kruglova Natalya Andreevna
Postgraduate student at the Department of Immunology, Faculty of Biology, Moscow State University. M.V. Lomonosov
Graduate of the Department of Immunology, Faculty of Biology, Moscow State University. Works under the direction of A.V. Filatova.
Head of the department: Sergey Arturovich Nedospasov – Doctor of Biological Sciences, Professor, Academician of the Russian Academy of Sciences.
Sergey Arturovich Nedospasov - Laureate of the State Prize of the Russian Federation (2015).
Areas of scientific interests:
– mechanisms of innate immunity;
– cytokines;
– regulation of transcription;
– cancer antigens;
– programmed cell death;
– reverse genetics.
Contacts
Directions of scientific research
- Mechanisms of innate immunity
- Mouse models of immunopathologies
- Physiology of the human and mouse immune system
- Transcription regulation in the immune system
- Homeostasis of the immune system
- Human cancer antigens
- Programmed cell death
- Immunity of aquatic organisms
- Mechanisms of phagocytosis
- Antibody bioengineering
- Immunobiotechnologies
The department annually accepts about 10 undergraduate students, 5–7 master’s students and about 5 graduate students.
In addition to departmental special courses, training at the Department of Immunology includes individual lectures by outstanding immunologists of our time. The theoretical training program in immunology at the department has no analogues not only in Russia, but also in the world. Experimental training takes place at workshops, summer practice at the White Sea Biological Station and in laboratories of leading research institutes associated with the department (see list below).
Most students' training includes internships abroad. For example, all 2015 graduates (9 students) had internships in leading research laboratories in Germany and the USA and all graduated from Moscow State University with honors.
The fundamental position of the department for the educational trajectory of its students is a fully completed education (bachelor’s, master’s, postgraduate) in the Moscow State University system. By the end of their graduate studies, our graduate students have lists of scientific papers that are outstanding in quantity and quality.
Department courses
Bachelor's degree:
- The logic of immune defense ( R.I.Ataullakhanov)
- Infections and immunity ( F.Yu.Gharib)
- Molecular evolution of defense systems ( E.S.Shilov)
- Oncoimmunology ( D.V.Kuprash, P.V.Belousov)
- Tumor cell biology ( N.L. Lazarevich)
- Cell energy ( V.D.Samuilov)
- Basics of genetic engineering ( I.N.Shatsky)
- Flow cytometry ( I.A.Vorobiev)
- Immunobiotechnologies ( A.V.Filatov)
Master's degree:
- Current problems of immunology
- Mechanisms of programmed cell death ( S.A. Nedospasov, E.S. Shilov)
- Molecular genetic basis for the formation of adaptive immunity ( Yu.B. Lebedev)
- Selected methods of data processing in biology / Fundamentals of programming ( A.V.Kitashov)
- Introduction to Mathematical Immunology ( G.A.Bocharov)
- Immunogenetics ( D.V.Kuprash, Yu.B.Lebedev, A.S.Apt)
- Immunomorphology ( A.P. Toptygina)
- Introduction to Clinical Immunology ( F.Yu.Gharib)
- Intercellular interactions ( A.V. Oleskin)
- Stem cells ( M.A. Lagarkova, N.I. Drize)
- Prospects for creating an HIV vaccine ( A.N.Vzorov)
Laboratories associated with the department and their heads
- Institute of Molecular Biology named after V.A.Engelhardt RAS
Laboratory of Molecular Mechanisms of Immunity ( S.A. Nedospasov)
Laboratory of intracellular signal transmission in normal and pathological conditions ( D.V.Kuprash) - Research Institute of Physico-Chemical Biology named after A.N. Belozersky MSU
Department of Molecular Immunology ( A.A. Kruglov) - Institute of Immunology FMBA
Laboratory of active immunity ( R.I.Ataullakhanov)
Laboratory of Immunochemistry ( A.V.Filatov) - Institute of Bioorganic Chemistry named after M.M. Shemyakin and Yu.A. Ovchinnikov RAS
Laboratory of Molecular Immunology ( S.M.Deev)
Laboratory of Cellular Interactions ( A.M.Sapozhnikov)